15 commercial spaces for rent in Panama as of October 23, 2026. Asking prices from US$1,500 to US$69,025 a month (median US$3,722 a month).
In a commercial space the lease is what matters: who the tenant is, how long is left, how the rent adjusts and who pays maintenance. The municipal land-use designation decides which businesses can operate there.
Asking prices from Panavanti's active inventory, not closing prices. Only commercial spaces for rent in Panama (n=15); the median is published with three or more listings.
| Active listings | 15 |
|---|---|
| Asking prices | Asking prices from US$1,500 to US$69,025 a month (median US$3,722 a month) |
| Areas | 49 m² to 3,288 m² |
| Median per m² | US$21 a month (n≥3) |
| Updated | October 23, 2026 |
Commercial Space for Rent in Santa María Plaza
Local comercial · 3,288 m²
US$69,025 a month
Commercial Space for Rent in the Heart of Calle 50
Local comercial · 422 m²
US$6,330 a month
Commercial Unit 18 for Rent in Santa María Plaza
Local comercial · 282 m²
US$5,640 a month
Commercial Unit 22 for Rent in Santa María Plaza
Local comercial · 149 m²
US$5,640 a month
Commercial Space for Rent in Plaza Midtown, San Francisco
Local comercial · 150 m²
US$4,500 a month
Commercial Unit 24 for Rent in Santa María Plaza
Local comercial · 625 m²
US$4,499 a month
Commercial Spaces for Rent in Callejón Soná, Casco Antiguo
Local comercial · 125 m²
US$4,170 a month
Commercial Unit 19 for Rent in Santa María Plaza
Local comercial · 207 m²
US$3,722 a month
Commercial Space for Rent in Plaza Midtown, San Francisco
Local comercial · 150 m²
US$3,500 a month
Commercial Unit 10 for Rent in Santa María Plaza
Local comercial · 77 m²
US$3,060 a month
Commercial Unit 13 for Rent in Santa María Plaza
Local comercial · 76 m²
US$3,054 a month
Commercial Space for Rent in Plaza Midtown, Ricardo J. Alfaro
Local comercial · 154 m²
US$2,700 a month
Commercial Space for Rent in Plaza Midtown, Tumba Muerto
Local comercial · 154 m²
US$2,600 a month
Commercial Space for Rent in Ocean Mall, Costa del Este
Local comercial · 120 m²
US$2,500 a month
Commercial Spaces for Rent in Plazuela Alfaro, Casco Antiguo
Local comercial · 49 m²
US$1,500 a month
Related guides: Buying property in Panama through a corporation (2026) · How to check property prices in Panama before you buy · Cap Rates in Panama: How to Calculate Them With 2026 Data · all guides
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